In pharmaceutical, food and chemical manufacturing, traditional separated granulation processes frequently bring multiple challenges: fragmented production steps, inconsistent particle quality, excessive fine powder, high binder consumption, low throughput, and difficulties meeting strict GMP compliance. Manufacturers producing herbal extracts, powder formulations and compound raw materials are also confronted with technical bottlenecks in stable granule formation.

Our newly developed LYSG-Series High-Efficiency Wet Mixing Granulator is designed to resolve these widespread production pain points. It integrates mixing, humidification and granulation into one continuous operation, simplifying your workflow and delivering consistent, reliable granule output. Widely adopted for pharmaceuticals, food, fine chemicals and metallurgical materials, the equipment stands out especially for processing herbal powder and Chinese herbal extracts, solving long-standing difficulties in herbal medicine granulation and earning consistent positive feedback from global users.

Core Advantages & How It Solves Your Production Challenges

✅ All-in-one integrated process, greatly enhanced productivity

Mixing and granulation are finished inside one closed vessel. The one-step process lifts production efficiency by 4–5 times compared with multi-stage traditional equipment. Produced granules are compact, uniform in size and feature high balling rate. Particle size and bulk density can be flexibly adjusted, perfectly adapted to herbal formulations with variable ratios of active ingredients and excipients.

✅ Siemens intelligent control system, stable batch-to-batch consistency

Equipped with Siemens PLC and touchscreen HMI, the machine supports stepless frequency conversion speed regulation and full automatic parameter management. Operators can preset temperature, running speed, duration and production formulas. The system automatically executes programs, lowering manual operation errors and ensuring consistent quality between batches.

✅ Optimized cutting & stirring structure, reduce fine powder waste

Combining traditional straight cutting blades with innovative V-shaped cutting knives, the unit performs both transverse and longitudinal cutting to shorten granulation cycles. The proprietary stirring paddle design effectively removes adhered materials on the vessel inner wall, reducing material buildup and particle collision against the tank surface. The fine powder content can be cut by up to 8%, minimizing raw material waste.

✅ Flexible binder feeding system, cut raw material consumption by around 20%

Standardly equipped with dripping and leakage-type binder feeding devices. You can choose dripping feeding or direct mixing according to different formulations. Precise binder addition lowers binder consumption by approximately 20% while achieving ideal mixing and granulation results.

✅ Jacket heating & cooling system, flexible temperature control

The jacketed tank structure supports material heating or cooling as required. Microcomputer automatic temperature control maintains temperature deviation within ±2°C, supporting diversified production processes for temperature-sensitive materials.

✅ Innovative shaft sealing design, low maintenance & long service life

The rotary shaft of stirring paddles and cutting knives adopts combined oil injection + air inflation double sealing structure. This design fundamentally solves the frequent shaft seal failure issue that troubles most conventional granulation equipment. The pull-out type shaft seal structure enables quick disassembly, convenient inspection and maintenance.

✅ Comprehensive safety & dust-free operation design

Multiple safety interlock protections are configured. The machine can only be started via password after the tank lid is closed, effectively protecting operators and equipment. The cover reserves vacuum feeding port, matched with dust removal device and binder injection port. An observable scraping monitoring window allows real-time tracking of granulation status, realizing dust-free closed production.

Suitable Application Scenarios

- Pharmaceutical industry: mixing and granulation of API powder, compound preparations, herbal extracts and herbal powder

- Food industry: granulation of food additives, nutritional supplements and solid beverage raw materials

- Chemical industry: processing of various powdered and pasty chemical raw materials

- Metallurgy industry: preparation of metallurgical powder particles

Working Principle

The equipment consists of main body, jacketed tank, tank cover, stirring paddle, cutting fly knife, discharge outlet, feeding system, transmission units, heating/cooling circuit and automatic control module.

The jacketed tank serves as the material container. Driven by transmission systems, stirring paddles rotate at preset speed to blend raw powder. Binder is added through the feeding unit to form wet mass within a short time. High-speed rotating cutting knives cut the wet mixture into target granules. Finally, the discharge valve opens for automatic discharging. By adjusting the rotation speed of stirring paddles and cutting knives, manufacturers can obtain granules with customized particle sizes.

If you are looking for stable, GMP-compliant wet granulation equipment to upgrade your production line, contact our team for customized technical solutions according to your raw material characteristics and batch requirements.